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Maria Ivanchenko

Maria Ivanchenko

Assistant Professor (Senior Research),
Ph.D., 1984 Insititute of Genetics, Moscow, Russia


Office/Lab:Cordley 4073/4066
Phone: 541-737-5306/5295

Research Area

Hormonal regulation of plant development.

Description of Research

The primary focus is on the auxin regulation of root development, which determines nutrient absorption and productivity, and a plant’s adaptation to specific soil environments. We use a variety of techniques in histology, molecular biology and genetics to place a novel type of auxin regulators, cyclophilin cis-trans protein isomerases, in the pathway that governs root architecture in tomato and the genetic plant model, Arabidopsis.

Histological images of tomato roots, illustrating absence of lateral root
primordia and abnormal auxin response in the cyclophilin-deficient
tomato mutant, diageotropica (dgt).


Maria G. Ivanchenko1,Jinsheng Zhu, Bangjun Wang, Eva Medvecká, Yunlong Du, Elisa Azzarello, Stefano Mancuso, Molly Megraw, Sergei Filichkin, Joseph G. Dubrovsky, Jiřı́Friml and Markus Geisler. 2015. The cyclophilin A DIAGEOTROPICA gene affects auxin transport in both root and shoot to control lateral root formation. Development 142, 712-721 doi:10.1242/dev.113225

Maria G. Ivanchenko, Désirée den Os, Gabriele B. Monshausen, Joseph G. Dubrovsky, Andrea Bednářová, and Natraj Krishnan (2013) Auxin increases the hydrogen peroxide (H2O2) concentration in tomato (Solanum lycopersicum) root tips while inhibiting root growth. Ann Bot 112, 1107–1116.

Santisree P., Nongmaithem S., Sreelakshmi Y., Ivanchenko M. and Sharma R. (2012) The root as a drill: An ethylene-auxin interaction facilitates root penetration in soil. Plant Signal. Behav. 7, 151-156. 


Santisree P., Nongmaihem S., Vasuki H., Sreelakshmi Y., Ivanchenko M.G., Sharma R. (2011) Tomato root penetration in soil requires a coaction between ethylene and auxin signaling. Plant Phys 156, 14241438.


DubrovskyJ.G., Napsucialy-MendivilS., Duclercq J., Cheng Y., Shishkova S., Ivanchenko M.G., FrimlJ., MurphyA.S., and Benkova,  E.(2011)Auxin minimum defines a developmental window for lateral root initiation. New Phyt 191, 970-983.


Ivanchenko M.G., Napsucialy-MendivilS. and Dubrovsky J.G. (2010) Auxin-induced inhibition of lateral root initiation contributes to root system shaping in Arabidopsis thaliana. Plant J 64, 740752. 

Benková E, Ivanchenko MG, Friml J, Shishkova S, and Dubrovsky JG (2009)A morphogenetic trigger: is there a new concept in plant developmental biology? Trends Plant Sci 14, 189-193

Dubrovsky JG, Soukup A, Napsucialy-Mendivivl S, Jeknic Z, and Ivanchenko MG (2009) Lateral Root Index: An integrative measure of primordium formation. Ann Botany 103, 807-817.

Dubrovsky JG, Sauer M, Napsucialy-Mendivil S, Ivanchenko MG, Friml J, Shishkova S, Celenza J, Benková E. (2008) Auxin acts as a local morphogenetic trigger to specify lateral root founder cells. Proc. Natl. Acad. Sci. U S A 105, 8790-8794.

Ivanchenko M.G., Muday G.K., Dubrovsky J.G. (2008) Ethylene-auxin interactions regulate lateral root initiation and emergence in Arabidopsis thaliana. Plant J. 55, 335-347.

Negi S., Ivanchenko M.G., Muday G.K. (2008) Ethylene regulates lateral root formation and auxin transport in Arabidopsis thaliana. Plant J. 55, 175-187.

Ivanchenko M., Coffeen W., Lomax T., Dubrovsky J.G., (2006) Mutations in the Diageotropica (Dgt) gene uncouple patterned cell division during lateral root initiation from proliferative cell division in the pericycle. Plant J. 46, 436-347.

Oh K., Ivanchenko M., White TJ, and Lomax T (2006) The Diageotropica gene of tomato encodes a cyclophilin, a novel player in auxin signaling. Planta 224,133- 144.

Oh K., Hardeman K., Ivanchenko M. G., Ellard-Ivey M., Nebenfur A., White T., Lomax T. L. (2002) Fine mapping in tomato using microsynteny with the Arabidopsis genome: the Diageotropica (Dgt) locus. Genome Biology 3:research0049.

Ivanchenko M., Stanewsky R., and Giebultowicz J.M. (2001) Circadian photoreception in Drosophila: functions of cryptochrome in peripheral and central clocks. J. Biol. Rhythms 16, 205-215.

Bixler L. M., Lerner J. P., Ivanchenko M., McCormic R. S., Barnes D. W., Bayne C. J. (2001) Axenic culture of Schistosoma mansoni sporocists in low O2 environments. J. Parasitol. 87, 1167-1168.

Ivanchenko M., Vejlupkova Z., Quatrano R. S., Fowler J. E. (2000) Maize ROP7 GTPase contains a unique, CaaX box-independent plasma membrane targeting signal. Plant J. 24, 79-90.

Ivanchenko M. G., Lerner J. P., McCormick R. S., Toumadje A., Allen B., Fischer K., Hedstrom O., Helmrich A., Barnes D. W., Bayne C. J. (1999). Continuous in vitro propagation and differentiation of cultures of the intramolluscan stages of the human parasite Schistosoma mansoni. Proc. Natl. Acad. Sci. USA 96, 4965-4970.

Ivanchenko M ., Yaneva J., and Zlatanova J. (1998) Interactions of histone H1 with supercoiled DNA: Electrophoretical and filter-binding studies. Biochimie 80, 1031-1034.

Ivanchenko M ., Zlatanova J., and van Holde K. (1997). Histone H1 preferentially binds to superhelical DNA molecules of higher compaction. Biophys. J . 72, 1388-1395.

Ivanchenko M . and Zlatanova J. (1997). Deoxyribonuclease I-facilitated electrotransfer of protein-DNA complexes from electrophoretic gels to nitrocellulose membranes. Electrophoresis 18, 72-73.

Ivanchenko M ., Hassan A., van Holde K., and Zlatanova J. (1996). H1 binding unwinds DNA: Evidence from topological assays. J. Biol. Chem . 271, 32580-32585.

Ivanchenko M ., Zlatanova J., Varga-Weiz P., Hassan A., and van Holde K. (1996). Linker histones affect patterns of digestion of supercoiled plasmids by single-strand-specific nucleases. Proc. Natl. Acad. Sc. USA 93, 6970-6974.

Ivanchenko M ., van Holde K., and Zlatanova J. (1996). Procaryotic DNA ligases unwind superhelical DNA. Biochem. Biophys. Res. Commun . 226, 498-505.

Rey E., Yaneva J., Ivanchenko M ., van Holde K., and Zlatanova J. (1996). Linker histones inhibit T4 and E. coli DNA ligases. Biochem. Biophs. Res. Commun. 222, 512-518.

Ivanchenko M . and Avramova Z. (1992). Interaction of MAR-sequences with nuclear matrix DNA. J. Cell. Biochem . 50, 190-200.

Stoilov L.M., Zlatanova J.S., Vassileva A.P., Ivanchenko M., Krachmarov, Ch. P. and Genchev D.D. (1988). Supercoils in plant DNA: Nucleoid sedimentation studies. J. Cell Sci . 89, 243-252.

Avramova Z., Ivanchenko M . and Tsanev R. (1988). A protein fraction stably linked to DNA in plant chromatin. Plant Mol. Biol . 11, 4401-4408.

Ivanchenko M . & Georgieva E. (1987). Electrophoretic heterogeneity of maize histones. Electrophoresis 9, 812-815.

Ivanchenko M., Georgieva E., Usheva A. and Avramova Z. (1987). A study on the heterogeneity of histone H1 from dry maize embryos. Eur. J. Biochem . 162, 339-344.