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The Uehling lab studies evolution of fungal interactions with other organisms, or symbioses. We focus on plant-root associated mutualistic (beneficial) fungi called mycorrhizae, human pathogenic (detrimental) fungi such as those associated with the disease Valley Fever, and bacteria that live inside of fungal cells, or endosymbionts. Our research relies heavily on generating, processing, and analyzing whole genome sequences and other genomic data to generate and test hypotheses.
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Students will learn to process and analyze whole genome sequence data. Tasks may include: isolating and sequencing fungal DNAs; assembling, and analyzing fungal genomes and transcriptomes; identifying genetic variation; phylogenomic analyses; assessing population structure and diversity; and evaluating evolutionary hypotheses using population diversity metrics from whole genome sequencing data.
Students will learn fundamental concepts in fungal symbiotic interactions, information flow, and genomics. Students will use fundamentals of computer science to leverage genomics data to ask and answer biological research questions.