Genomics, Transcriptomics, Plant system biology, Plant metabolic networks, Cell signaling, Self-incompatibility, and Organelle biogenesis.
Functional genomics of S-domain Receptor-like Kinase subfamily in plants
Receptors-like kinases (RLKs) are major players in perceiving and transducing extracellular signals into appropriate cellular responses in plants. Fully sequenced plant genomes suggest that RLKs form one of the largest gene families in plants. However, function of majority of RLKs and their interactions with other proteins are unknown. My laboratory is interested in analyzing the second largest subfamily of RLKs known as “S-Domain” (SD)-RLKs, so named because its members share sequence and structural similarity with the extracellular-ligand binding domain or “S Domain” of the S-locus receptor kinase, SRK.
Development and Curation of Plant Pathways Databases
As more plant genomes are getting sequenced, complementary system-level metabolic, genetic and signaling networks must be developed to discover spatial, temporal, and developmental changes in plant’s metabolism and how it’s affected by various biotic and abiotic stresses. Species-specific metabolic pathway databases can provide a framework to score differences among cultivars and across plant species, and thus, can foster discoveries of novel interaction among genes, gene products, and metabolites. Some of the Plant metabolic pathway databases developed by our group are available here.
Research Group Members
2014-present Christina M. Partipilo
2014-present Kelsey M. Nadeau
2013-2014 Eli N. Waddell
2013 Kate Threlfall
2009-2011 Alnakhli, Ali
2008-2009 Jimmy Hoang
2008-2009 Tracy Nguyen